Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257242 | 1.00 | LMNA (0.52) | LMNAMAPK1HTTL3MBTL1CA9 | |
| Benzene SCHEMBL28280701 | 1.00 | LMNA (0.52) | LMNAMAPK1HTTL3MBTL1CA9 | |
| SCHEMBL45278 | 1.00 | LMNA (0.52) | LMNAMAPK1HTTL3MBTL1CA9 | |
| SCHEMBL28059930 | 0.97 | LMNA (0.50) | LMNAMAPK1HTTL3MBTL1CA9 | |
| SCHEMBL27945945 | 0.97 | LMNA (0.50) | LMNAMAPK1HTTL3MBTL1CA9 | |
| SCHEMBL11235227 | 0.97 | LMNA (0.50) | LMNAMAPK1HTTL3MBTL1CA9 | |
| Water SCHEMBL4312372 | 0.97 | LMNA (0.50) | LMNAMAPK1HTTL3MBTL1CA9 | |
| SCHEMBL11266105 | 0.97 | LMNA (0.50) | LMNAMAPK1HTTL3MBTL1CA9 | |
| SCHEMBL4279171 | 0.95 | CA9 (0.48) | LMNAMAPK1HTTL3MBTL1CA9 | |
| Methoxymethane SCHEMBL25296693 | 0.93 | LMNA (0.52) | LMNAMAPK1HTTL3MBTL1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12358907-B2 | Substituted pyrrolidine amides III | Grünenthal GmbH (DE) | 2025-07-15 | — | — | US | disclosed |
| US-20250197898-A1 | ISOTHIOCYANATE CONTAINING BRASSICACEAE PRODUCTS AND METHOD OF PREPARATION THEREOF | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2025-06-19 | — | — | US | disclosed |
| US-12227780-B2 | Isothiocyanate containing Brassicaceae products and method of preparation thereof | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2025-02-18 | — | — | US | disclosed |
| CN-113382990-B | Substituted pyrrolidinamide III | 格吕伦塔尔有限公司 | 2024-11-19 | — | — | CN | disclosed |
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | CORTEVA AGRISCIENCE LLC (US) | 2024-04-18 | — | — | US | disclosed |
| CN-117813004-A | Auxin herbicide and application method thereof | 科迪华农业科技有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-29 | — | — | US | disclosed |
| WO-2024031002-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | CORTEVA AGRISCIENCE LLC (US) | 2024-02-08 | — | — | WO | disclosed |
| CN-116789598-A | 3-alkenyl isoquinoline 2-oxide compound and preparation method thereof | 广州大学 | 2023-09-22 | — | — | CN | disclosed |
| US-11753353-B2 | PBX composition | BAE SYSTEMS PLC (GB) | 2023-09-12 | — | — | US | disclosed |
| US-20050070584-A1 | Substituted aryloximes | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
| EP-1223167-A2 | Substituted isoxazoles for the treatment of inflammation | G.D. Searle & Co. (US) | 2002-07-17 | — | — | EP | disclosed |
| US-5763640-A | OXIMINOMETHYLPHENYL DERIVATIVES | ZENECA LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0370629-B2 | Fungicides | ZENECA LTD (GB) | 1998-01-07 | — | — | EP | disclosed |
| US-5631253-A | FUNGICIDES, INSECTICIDES AND MITICIDES USING METHYLOXIME PHENYLPROPENOIC ACID | ZENECA LIMITED (GB) | 1997-05-20 | — | — | US | disclosed |
| US-5432197-A | Insecticidal, miticidal | ZENECA LIMITED (GB) | 1995-07-11 | — | — | US | disclosed |
| US-5371084-A | Insecticides and miticides | ZENECA LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0506149-A2 | Fungicides | ZENECA LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| US-5055471-A | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0370629-A1 | Fungicides | ZENECA LIMITED (GB) | 1990-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358907-B2 | Substituted pyrrolidine amides III | NR3C1, NR3C2, MC2R | LMNA 4699/4885MAPK1 1105/4885HTT 3853/4885 |
| US-20240122179-A1 | AUXINIC HERBICIDES AND METHODS OF USE THEREOF | DDT, HACL2, ALAD | LMNA 4370/4885MAPK1 4454/4885HTT 694/4885 |
| US-20050070584-A1 | Substituted aryloximes | AHR, NQO1, AOX1 | LMNA 2902/4885MAPK1 3843/4885HTT 2032/4885 |
| US-20240067632-A1 | WEE1 Degrading Compounds and Uses Thereof | WEE1, WEE2, PPME1 | LMNA 2661/4885MAPK1 1317/4885HTT 3375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.