SCHEMBL28114260

SCHEMBL28114260

O=C(O)c1ccccc1S(=O)O.[NaH].[NaH]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
TDP1 Q9NUW8 1/20 0.58
KDM4E B2RXH2 2/20 0.56
ALOX15 P16050 1/20 0.54
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA4 P22748 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
HMGB1 P09429 1/20 0.46
HPGD P15428 1/20 0.46
CA6 P23280 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MAPT P10636 3/20 0.45
HDAC8 Q9BY41 1/20 0.45
POLB P06746 1/20 0.43
AKR1C3 P42330 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778596 0.98 ALDH1A1 (0.60) ALDH1A1TDP1KDM4EALOX15CA12
Phthalic Acid SCHEMBL28147268 0.81 ALDH1A1 (0.74) ALDH1A1TDP1KDM4EALOX15CA12
SCHEMBL9133477 0.80 ALDH1A1 (0.60) ALDH1A1TDP1KDM4EALOX15CA12
SCHEMBL9133128 0.80 ALDH1A1 (0.60) ALDH1A1TDP1KDM4EALOX15CA12
SCHEMBL9130954 0.80 ALDH1A1 (0.60) ALDH1A1TDP1KDM4EALOX15CA12
SCHEMBL9133227 0.80 ALDH1A1 (0.60) ALDH1A1TDP1KDM4EALOX15CA12
SCHEMBL9133911 0.80 ALDH1A1 (0.60) ALDH1A1TDP1KDM4EALOX15CA12
SCHEMBL14124798 0.79 AKR1C3 (0.55) ALDH1A1TDP1KDM4EMAPTAKR1C3
SCHEMBL7994220 0.79 ALDH1A1 (0.46) ALDH1A1TDP1KDM4EALOX15CA12
SCHEMBL28007602 0.78 ALDH1A1 (0.44) ALDH1A1TDP1KDM4EALOX15CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117112-A One prepare (±) 2 azabicyclos [2,2,1] heptan 5 alkene 3 ketone method 营口三征新科技化工有限公司 2016-11-16 CN disclosed