SCHEMBL28007602

SCHEMBL28007602

CC(=O)c1ccccc1S(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 1/20 0.38
KMT2A Q03164 3/20 0.37
PBRM1 Q86U86 1/20 0.37
MEN1 O00255 1/20 0.37
NSD2 O96028 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
MCL1 Q07820 1/20 0.37
ALOX15 P16050 1/20 0.37
G6PD P11413 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778596 0.80 ALDH1A1 (0.60) ALDH1A1TDP1KDM4ESMN1; SMN2HPGD
SCHEMBL29084161 0.78 ALDH1A1 (0.50) ALDH1A1TDP1KDM4ELMNAHPGD
SCHEMBL26213652 0.78 ALDH1A1 (0.40) ALDH1A1TDP1KDM4ESMN1; SMN2HPGD
SCHEMBL28114260 0.78 ALDH1A1 (0.58) ALDH1A1TDP1KDM4ESMN1; SMN2HPGD
SCHEMBL11065639 0.78 LMNA (0.55) ALDH1A1KDM4ELMNAKMT2APOLB
SCHEMBL18903282 0.78 GAA (0.53) ALDH1A1TDP1POLBBRD4
SCHEMBL9153083 0.75 G6PD (0.50) ALDH1A1TDP1KDM4ESMN1; SMN2LMNA
SCHEMBL279655 0.75 ALDH1A1 (0.53) ALDH1A1TDP1KDM4ESMN1; SMN2LMNA
SCHEMBL14124798 0.75 AKR1C3 (0.55) ALDH1A1TDP1KDM4ELMNAKMT2A
SCHEMBL11373632 0.73 ALDH1A1 (0.50) ALDH1A1TDP1KDM4ESMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628606-A Preparation method of sulfohydrazide compound WANG HUA 2015-05-20 CN claimed
CN-104628606-A Preparation method of sulfohydrazide compound WANG HUA 2015-05-20 CN disclosed