Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28197374 | 0.87 | — | — | |
| Methane SCHEMBL28185612 | 0.87 | — | — | |
| Methane SCHEMBL5586176 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL27538421 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL28889575 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL28585385 | 0.75 | GPR39 (0.50) | — | |
| Hydrochloric Acid SCHEMBL6914388 | 0.71 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL14738839 | 0.71 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL444225 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL704 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317154-A | Method for preparing 17alpha-hydroxyprogesterone | 浙江仙琚制药股份有限公司 | 2017-01-11 | — | — | CN | disclosed |