Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114428 | 1.00 | KDM4E (0.48) | KDM4EPOLBHRH3CHRNB2CHRNA4 | |
| SCHEMBL14779735 | 0.85 | FAAH (0.50) | — | |
| SCHEMBL14779737 | 0.85 | FAAH (0.50) | — | |
| SCHEMBL27958431 | 0.82 | KDM4E (0.56) | KDM4EPOLBHRH3CHRNB2CHRNA4 | |
| SCHEMBL27958432 | 0.82 | KDM4E (0.56) | KDM4EPOLBHRH3CHRNB2CHRNA4 | |
| SCHEMBL14780344 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL14780346 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL21937561 | 0.77 | KDM4E (0.60) | KDM4EPOLBHRH3CHRNB2CHRNA4 | |
| SCHEMBL4310630 | 0.75 | FAAH (0.53) | KDM4EPOLBCHRNB2CHRNA4CHRNA7 | |
| SCHEMBL4310635 | 0.75 | FAAH (0.53) | KDM4EPOLBCHRNB2CHRNA4CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103814021-B | Dihydroquinoline 2 ketone derivatives | 霍夫曼-拉罗奇有限公司 | 2016-12-21 | — | — | CN | disclosed |