⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24730 | 0.73 | — | — | |
| SCHEMBL31710472 | 0.71 | — | — | |
| SCHEMBL21737049 | 0.67 | — | — | |
| SCHEMBL1662549 | 0.67 | — | — | |
| SCHEMBL601234 | 0.66 | HCAR2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL2692202 | 0.65 | — | — | |
| SCHEMBL21081222 | 0.64 | — | — | |
| SCHEMBL21998128 | 0.62 | — | — | |
| SCHEMBL26855703 | 0.62 | — | — | |
| SCHEMBL9280097 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114555-B | Pyrazolopyrimidine derivatives, process for their preparation and their therapeutic use | 赛诺菲 | 2017-09-01 | — | — | CN | disclosed |
| CN-106317056-A | Pyrazolopyridine derivatives, preparation process therefor and therapeutic use thereof | 赛诺菲 | 2017-01-11 | — | — | CN | disclosed |