Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098683 | 0.82 | IDO1 (0.35) | — | |
| SCHEMBL20162355 | 0.82 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL950254 | 0.80 | HCAR2 (0.39) | HCAR2KDM4ELMNA | |
| SCHEMBL6922497 | 0.74 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL614565 | 0.72 | — | — | |
| SCHEMBL3979218 | 0.72 | — | — | |
| SCHEMBL16209016 | 0.72 | KDM4E (0.36) | HCAR2KDM4ELMNA | |
| SCHEMBL69630 | 0.70 | ALDH1A1 (0.39) | HCAR2KDM4ELMNA | |
| SCHEMBL353093 | 0.70 | — | — | |
| SCHEMBL950861 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269340-A | KCNT1 inhibitors and methods of use | 普拉克西斯精密药物股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-101535274-B | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE | 2012-09-05 | — | — | CN | disclosed |
| US-8115012-B2 | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20100069646-A1 | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| CN-101535274-A | Process for preparing difluoromethylpyrazolyl carboxylates | BASF SE (DE) | 2009-09-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069646-A1 | Process for preparing difluoromethylpyrazolyl carboxylates | HCN2, HCN3, C9 | HCAR2 3034/4885KDM4E 1030/4885LMNA 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.