Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365254 | 0.93 | SIGMAR1 (0.55) | KCNH2 | |
| SCHEMBL28114160 | 0.88 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL28114575 | 0.87 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL28114153 | 0.84 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL28369155 | 0.80 | KCNH2 (0.80) | KCNH2 | |
| SCHEMBL238887 | 0.74 | SIGMAR1 (0.54) | — | |
| SCHEMBL28114172 | 0.74 | HTT (0.59) | — | |
| SCHEMBL31466386 | 0.74 | SIGMAR1 (0.78) | KCNH2 | |
| SCHEMBL28365591 | 0.73 | KCNH2 (0.79) | KCNH2 | |
| SCHEMBL6988597 | 0.72 | SIGMAR1 (0.53) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111153859-B | Pyridazinone derivative and application thereof | 江苏恩华药业股份有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-111153859-A | Pyridazinone derivative and application thereof | 江苏恩华药业股份有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-106146404-B | Pyridazinone derivative and application thereof | 江苏恩华药业股份有限公司 | 2020-03-20 | — | — | CN | disclosed |
| CN-106146404-A | Pyridazinone derivative and application thereof | 江苏恩华药业股份有限公司 | 2016-11-23 | — | — | CN | disclosed |