Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28114160 | 0.89 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL28114566 | 0.87 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL28365254 | 0.80 | SIGMAR1 (0.55) | KCNH2 | |
| SCHEMBL28114172 | 0.78 | HTT (0.59) | — | |
| SCHEMBL28365591 | 0.76 | KCNH2 (0.79) | KCNH2 | |
| SCHEMBL13219371 | 0.75 | HTT (0.70) | — | |
| SCHEMBL9387596 | 0.75 | ALDH1A1 (0.47) | KCNH2 | |
| SCHEMBL29502121 | 0.74 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL28114577 | 0.73 | KCNH2 (0.94) | KCNH2 | |
| SCHEMBL28114576 | 0.72 | AVPR2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146404-A | Pyridazinone derivative and application thereof | 江苏恩华药业股份有限公司 | 2016-11-23 | — | — | CN | disclosed |