Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | STAMBP | O95630 | 1/20 | 0.47 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4987651 | 0.79 | KDM4E (0.38) | SMN1; SMN2LMNAKDM4EMEN1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5265639 | 0.79 | PSMD14 (0.45) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| SCHEMBL2561709 | 0.76 | PSMD14 (0.46) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| SCHEMBL29755236 | 0.76 | PSMD14 (0.46) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| SCHEMBL25521847 | 0.76 | PSMD14 (0.40) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| SCHEMBL163182 | 0.75 | PSMD14 (0.56) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| SCHEMBL27599972 | 0.74 | PSMD14 (0.55) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14966721 | 0.74 | PSMD14 (0.55) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| SCHEMBL6786132 | 0.73 | PSMD14 (0.40) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 | |
| SCHEMBL160862 | 0.71 | HPGDS (0.44) | PSMD14STAMBPCOPS5NNMTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781251-B | Can as kinase modulator through the substituted pyridinyl compounds of bicyclic heterocycle | 百时美施贵宝公司 | 2016-12-14 | — | — | CN | disclosed |