Dimethylcarbate

Dimethylcarbate

SCHEMBL28114749

CN(C)C(=O)O.NC(=O)O.NC(=O)O.NC(=O)O.NC(=O)O.NC(=O)O.[Zn]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
PMP22 Q01453 2/20 0.38
LMNA P02545 2/20 0.38
ALOX15 P16050 1/20 0.38
BLM P54132 1/20 0.38
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35
NFKB1 P19838 1/20 0.35
THPO P40225 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 1/20 0.35
APEX1 P27695 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
OR51E2 Q9H255 1/20 0.33
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylcarbate SCHEMBL5803957 0.96 ACHE (0.54) ACHEALDH1A1TSHRPMP22LMNA
Dimethylcarbate SCHEMBL5998761 0.90 ACHE (0.47) ACHEALDH1A1TSHRPMP22LMNA
Dimethylcarbate SCHEMBL1873907 0.89
Dimethylcarbate SCHEMBL1232328 0.84
Dimethylcarbate SCHEMBL15360 0.84
Dimethylcarbate SCHEMBL6868663 0.81
Dimethylcarbate SCHEMBL4290346 0.81
Dimethylcarbate SCHEMBL3695848 0.81
Dimethylcarbate SCHEMBL11751711 0.81
Dimethylcarbate SCHEMBL321621 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106317643-A Novel compound used for cable materials 刘夕平 2017-01-11 CN disclosed