Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640695 | 1.00 | TSHR (0.35) | TSHRLMNATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL3672565 | 0.90 | CHRM2 (0.33) | TSHRLMNATP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL2543856 | 0.89 | CHRM2 (0.36) | TSHRCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL3678402 | 0.88 | EPHX1 (0.34) | ALDH1A1CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL3678399 | 0.88 | EPHX1 (0.34) | ALDH1A1CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2642444 | 0.85 | — | — | |
| SCHEMBL880204 | 0.84 | — | — | |
| SCHEMBL24884685 | 0.83 | EPHX1 (0.36) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL868024 | 0.83 | EPHX1 (0.36) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL20839586 | 0.83 | EPHX1 (0.36) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106119303-A | A kind of protease splits the method for preparation chirality 3 cyclohexene 1 formic acid | 浙江工业大学 | 2016-11-16 | — | — | CN | claimed |
| CN-116355876-A | Recombinant esterase mutant, engineering bacterium and application thereof in synthesis of (S) -3-cyclohexene-1-formic acid | 浙江工业大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-112813131-B | Carboxylesterase and application thereof in producing cyclohexenecarboxylic acid by kinetic resolution of cyclohexeneformate | 江南大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-112813131-A | Carboxylesterase and application thereof in producing cyclohexenecarboxylic acid by kinetic resolution of cyclohexenecarboxylate | 江南大学 | 2021-05-18 | — | — | CN | disclosed |
| CN-106119303-B | Method for preparing chiral 3-cyclohexene-1-formic acid by protease resolution | 浙江工业大学 | 2020-02-21 | — | — | CN | disclosed |
| CN-106119303-B | Method for preparing chiral 3-cyclohexene-1-formic acid by protease resolution | 浙江工业大学 | 2020-02-21 | — | — | CN | disclosed |
| CN-106119303-A | A kind of protease splits the method for preparation chirality 3 cyclohexene 1 formic acid | 浙江工业大学 | 2016-11-16 | — | — | CN | disclosed |