Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.71 |
| ▸ | ABAT | P80404 | 1/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601429 | 0.86 | ALDH5A1 (0.67) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| SCHEMBL244093 | 0.83 | ALDH5A1 (1.00) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| Iodomethane SCHEMBL27504663 | 0.82 | ALDH5A1 (0.90) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| SCHEMBL5661502 | 0.81 | ALDH5A1 (0.71) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| SCHEMBL10920512 | 0.80 | EGFR (0.73) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| SCHEMBL10920508 | 0.80 | EGFR (0.73) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| SCHEMBL27932094 | 0.79 | ALDH1A1 (0.56) | ALDH5A1ABATALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29737122 | 0.79 | ALDH5A1 (0.67) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| SCHEMBL11239202 | 0.79 | EGFR (0.72) | ALDH5A1ABATEGFRALDH1A1MAPK1 | |
| SCHEMBL11851919 | 0.79 | EGFR (0.72) | ALDH5A1ABATEGFRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132422-A | Adoptive cell therapy using agonists of retinoic acid receptor-associated orphan receptor gamma & related therapeutic methods | 莱斯拉公司 | 2016-11-16 | — | — | CN | disclosed |