Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133153 | 0.86 | — | — | |
| SCHEMBL1446235 | 0.83 | — | — | |
| SCHEMBL30442526 | 0.83 | — | — | |
| SCHEMBL28821908 | 0.83 | — | — | |
| Benzene SCHEMBL5529179 | 0.78 | ALDH1A1 (0.82) | ALDH1A1TDP1MEN1LMNABLM | |
| Dimethyl Sulfoxide SCHEMBL28219568 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TDP1MEN1LMNABLM | |
| Tromethamine SCHEMBL1890834 | 0.70 | ALDH1A1 (0.67) | ALDH1A1TDP1MEN1LMNABLM | |
| Dimethyl Sulfoxide SCHEMBL11881662 | 0.70 | — | — | |
| Dimethyl Sulfoxide SCHEMBL23041043 | 0.69 | TSHR (0.46) | ALDH1A1TSHR | |
| Dimethyl Sulfoxide SCHEMBL379695 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317861-A | PVDF (Polyvinylidene Fluoride)/polyamide composite material used for 3D (Three-dimensional) printing, and preparation method and application thereof | 上海辰云信息科技有限公司 | 2017-01-11 | — | — | CN | disclosed |