Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25385523 | 0.86 | PSMD14 (0.43) | PSMD14POLBALDH1A1MAPK10PPARG | |
| SCHEMBL30314598 | 0.78 | ALDH1A1 (0.40) | PSMD14POLBALDH1A1MAPK10PPARG | |
| SCHEMBL24050550 | 0.78 | ALDH1A1 (0.40) | PSMD14POLBALDH1A1MAPK10PPARG | |
| SCHEMBL20951908 | 0.74 | PSMD14 (0.43) | PSMD14POLBALDH1A1MAPK10PPARG | |
| SCHEMBL1505593 | 0.72 | MAPK1 (0.53) | PSMD14POLBALDH1A1MAPK10PPARG | |
| SCHEMBL28115459 | 0.71 | PSMD14 (0.43) | PSMD14POLBALDH1A1KMT2AMAPK1 | |
| SCHEMBL20605105 | 0.71 | PSMD14 (0.70) | PSMD14POLBALDH1A1GAATSHR | |
| SCHEMBL197929 | 0.70 | MAPK1 (0.51) | PSMD14POLBALDH1A1MAPK10PPARG | |
| SCHEMBL30414233 | 0.70 | MAPK1 (0.51) | PSMD14POLBALDH1A1MAPK10PPARG | |
| SCHEMBL335911 | 0.70 | MAPK1 (0.51) | PSMD14POLBALDH1A1MAPK10PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117205-A | Pyrazolo spiral shell ketone derivatives as S-acetyl-coenzyme-A carboxylase inhibitor class | 辉瑞大药厂 | 2016-11-16 | — | — | CN | disclosed |