Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251722 | 0.85 | HSP90AA1 (0.38) | — | |
| SCHEMBL27830398 | 0.83 | HSP90AA1 (0.36) | — | |
| Tromethamine SCHEMBL5488401 | 0.68 | MEN1 (0.40) | — | |
| Piperazine SCHEMBL5653848 | 0.68 | HIF1A (0.50) | — | |
| Piperazine SCHEMBL9284358 | 0.68 | HIF1A (0.50) | — | |
| Sulfuric Acid Dimethyl Ester SCHEMBL5069842 | 0.67 | — | — | |
| SCHEMBL28104380 | 0.64 | CCNB2 (0.31) | — | |
| SCHEMBL28146724 | 0.62 | HSP90AA1 (0.38) | — | |
| SCHEMBL1436986 | 0.61 | HDAC8 (0.35) | — | |
| SCHEMBL1721866 | 0.61 | HSP90AA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336739-A | Pigment dispersion for color filter, coloring composition for color filter, color filter and display device | DNP精细化工股份有限公司 | 2017-01-18 | — | — | CN | disclosed |