Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690473 | 0.77 | DAO (0.65) | FLT3HRH4ALDH1A1KDM4EDAO | |
| SCHEMBL28114699 | 0.75 | HRH4 (0.44) | AHRHRH4IMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL21356683 | 0.75 | AHR (0.45) | FLT3AHRHRH4NOS1AXL | |
| SCHEMBL28238792 | 0.75 | AOC3 (0.47) | FLT3AHRHRH4NOS1AXL | |
| SCHEMBL27889601 | 0.75 | DAO (0.62) | FLT3HRH4IMPDH2IMPDH1AURKA | |
| SCHEMBL31098173 | 0.75 | GAA (0.50) | FLT3AHRHRH4NOS1AXL | |
| SCHEMBL470317 | 0.75 | AHR (0.45) | FLT3AHRHRH4NOS1AXL | |
| SCHEMBL31070422 | 0.75 | AHR (0.45) | FLT3AHRHRH4NOS1AXL | |
| SCHEMBL19373476 | 0.75 | DAO (0.62) | FLT3AHRIMPDH2IMPDH1ALDH1A1 | |
| SCHEMBL27277840 | 0.75 | DAO (0.62) | FLT3HRH4NOS1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220551-A | The synthetic method of 4 bromine 2 oxyindoles | 叶芳 | 2016-12-14 | — | — | CN | claimed |
| CN-106220551-A | The synthetic method of 4 bromine 2 oxyindoles | 叶芳 | 2016-12-14 | — | — | CN | disclosed |