Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115668 | 0.86 | TGFBR1 (0.51) | TGFBR1CYP3A4CYP2C8KDM1A | |
| SCHEMBL13728992 | 0.80 | CYP11B1 (0.49) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL27808852 | 0.78 | NPC1 (0.37) | TGFBR1KDM1ADHODHTRPV3GABRA1 | |
| SCHEMBL13017142 | 0.77 | CYP11B1 (0.41) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL12320871 | 0.76 | NPC1 (0.49) | CYP11B1CYP11B2MAPK14 | |
| SCHEMBL19237528 | 0.75 | CYP11B1 (0.44) | KDM1ATRPV3CYP11B1CYP11B2 | |
| SCHEMBL14018473 | 0.75 | KDM1A (0.44) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL13062796 | 0.74 | CYP11B1 (0.44) | L3MBTL1CASP3SENP8SENP7SENP6 | |
| SCHEMBL12320870 | 0.74 | HPGDS (0.52) | TRPV3CYP11B1 | |
| SCHEMBL13602061 | 0.74 | CCR1 (0.46) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132950-A | Compounds and methods of use | 麦迪韦逊技术股份有限公司 | 2016-11-16 | — | — | CN | disclosed |