Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115268 | 0.87 | KDM4E (0.44) | HTR1ASLC6A2SLC6A4KDM4EP2RX3 | |
| SCHEMBL5764883 | 0.83 | TRPA1 (0.54) | HTR1ASLC6A2SLC6A4KDM4ETRPA1 | |
| SCHEMBL28115716 | 0.81 | TRPA1 (0.48) | KDM4ECD274TRPA1L3MBTL1RAF1 | |
| SCHEMBL24741603 | 0.81 | MEN1 (0.54) | KDM4ECD274TRPA1PDE4APDE4B | |
| SCHEMBL30108336 | 0.81 | MEN1 (0.54) | KDM4ECD274TRPA1PDE4APDE4B | |
| SCHEMBL2427966 | 0.81 | POLB (0.46) | SLC6A4KDM4ECD274TRPA1PDE4A | |
| SCHEMBL2031647 | 0.81 | ALDH1A1 (0.49) | SLC6A2SLC6A4KDM4ECD274PDE4A | |
| SCHEMBL28115267 | 0.79 | KDM4E (0.43) | KDM4EP2RX3CD274TRPA1PDE4A | |
| SCHEMBL18984674 | 0.79 | MEN1 (0.59) | HTR1ASLC6A2SLC6A4KDM4ECD274 | |
| SCHEMBL28440365 | 0.77 | NPC1 (0.45) | KDM4EP2RX3L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844399-B | A kind of method synthesizing 2-fluorophenol compound | 浙江工业大学 | 2016-12-07 | — | — | CN | disclosed |