Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722504 | 1.00 | KMT2A (0.69) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| SCHEMBL3819701 | 0.89 | KMT2A (0.71) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| SCHEMBL10894686 | 0.86 | KMT2A (0.68) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| SCHEMBL3963197 | 0.86 | KMT2A (0.68) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| SCHEMBL4418666 | 0.85 | KMT2A (0.66) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| Nicaraven SCHEMBL677580 | 0.85 | KMT2A (0.66) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| SCHEMBL5553293 | 0.85 | KMT2A (0.66) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| Nicaraven SCHEMBL31420006 | 0.85 | KMT2A (0.66) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| SCHEMBL26604262 | 0.84 | KMT2A (0.61) | KMT2AMEN1THRBEPHX2CYP1A2 | |
| SCHEMBL26604260 | 0.84 | KMT2A (0.61) | KMT2AMEN1THRBEPHX2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109045032-A | Aminopyridines and application method | 麦迪威森技术有限责任公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-106132950-B | Aminopyridines and methods of use | 麦迪威森技术有限责任公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-106132950-A | Compounds and methods of use | 麦迪韦逊技术股份有限公司 | 2016-11-16 | — | — | CN | disclosed |