Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nicaraven SCHEMBL677580 | 1.00 | KMT2A (0.66) | KMT2AMEN1LMNAALDH1A1THRB | |
| Nicaraven SCHEMBL9346555 | 0.96 | LMNA (0.63) | KMT2AMEN1LMNAALDH1A1THRB | |
| Nicaraven SCHEMBL9345911 | 0.92 | KMT2A (0.57) | KMT2AMEN1LMNAALDH1A1THRB | |
| Nicaraven SCHEMBL9345376 | 0.92 | KMT2A (0.57) | KMT2AMEN1LMNAALDH1A1THRB | |
| SCHEMBL3819701 | 0.86 | KMT2A (0.71) | KMT2AMEN1LMNAALDH1A1THRB | |
| SCHEMBL9346961 | 0.86 | KMT2A (0.60) | KMT2AMEN1LMNAALDH1A1THRB | |
| SCHEMBL9345939 | 0.86 | LMNA (0.55) | KMT2AMEN1LMNAALDH1A1THRB | |
| SCHEMBL24567733 | 0.85 | LMNA (0.67) | KMT2AMEN1LMNAALDH1A1THRB | |
| SCHEMBL8722504 | 0.85 | KMT2A (0.69) | KMT2AMEN1LMNAALDH1A1THRB | |
| SCHEMBL21467402 | 0.85 | LMNA (0.67) | KMT2AMEN1LMNAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034606-A2 | A CLINICALLY-TRANSLATABLE ROS/RNS MOLECULAR IMAGING AGENT USING A RADIOLABELED DERIVATIVE OF EDARAVONE (EDV) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2025-02-13 | — | — | WO | disclosed |