Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819701 | 0.86 | KMT2A (0.71) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL21082064 | 0.86 | KMT2A (0.71) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL8722504 | 0.85 | KMT2A (0.69) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL28115750 | 0.85 | KMT2A (0.69) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL26604260 | 0.85 | KMT2A (0.61) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL26604262 | 0.85 | KMT2A (0.61) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL3963197 | 0.84 | KMT2A (0.68) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL10894686 | 0.84 | KMT2A (0.68) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL27889626 | 0.83 | KMT2A (0.60) | KMT2AMEN1THRBEPHX2CYP2C9 | |
| SCHEMBL10767093 | 0.82 | NPC1 (0.59) | KMT2AEPHX2RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458403-A | insecticidal composition | DOW AGROSCIENCES LLC | 2012-05-16 | — | — | CN | disclosed |
| US-20090318396-A1 | CORTICOSTEROID LINKED BETA-AGONIST COMPOUNDS FOR USE IN THERAPY | GILEAD SCIENCES, INC. (US) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318396-A1 | CORTICOSTEROID LINKED BETA-AGONIST COMPOUNDS FOR USE IN THERAPY | ADRB1, ADRB2, ADRB3 | KMT2A 4412/4885MEN1 3670/4885THRB 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.