Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396523 | 0.85 | KDM4E (0.45) | KDM4EGPR3ERN1ALDH1A1GLA | |
| SCHEMBL3394680 | 0.81 | KDM4E (0.42) | KDM4EGPR3ERN1ALDH1A1GLA | |
| SCHEMBL15045826 | 0.81 | ERN1 (0.46) | KDM4EGPR3ERN1ALDH1A1GLA | |
| SCHEMBL27486500 | 0.79 | PARP1 (0.40) | KDM4EALDH1A1HPGDPDE10A | |
| SCHEMBL28237654 | 0.78 | MAOA (0.45) | KDM4EGPR3ERN1ALDH1A1GLA | |
| SCHEMBL11069998 | 0.77 | ERN1 (0.39) | KDM4EGPR3ERN1ALDH1A1GLA | |
| SCHEMBL28248094 | 0.76 | CYP1A2 (0.42) | KDM4EALDH1A1GAACYP1A2ADRA2A | |
| SCHEMBL27475492 | 0.76 | FERMT2 (0.36) | KDM4E | |
| SCHEMBL27434748 | 0.76 | — | — | |
| SCHEMBL7850047 | 0.76 | TLR7 (0.43) | KDM4EALDH1A1GLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187887-B | The preparation method of 4- oxyquinoline -3- formic acid | 上海工程技术大学 | 2018-08-14 | — | — | CN | claimed |
| CN-108623589-A | A kind of tetracyclic lactam class compound and its preparation method and application | 中国海洋大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108623588-A | A kind of tetracyclic and its preparation method and application containing lactams | 中国海洋大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108623561-A | A method of preparing piperazine Nino acid compound | 中国海洋大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108623581-A | A method of preparing piperazine Nino peace compound | 中国海洋大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108623562-A | A kind of quinolinone alkaloid class compound and its preparation method and application | 中国海洋大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-106187887-B | The preparation method of 4- oxyquinoline -3- formic acid | 上海工程技术大学 | 2018-08-14 | — | — | CN | disclosed |
| CN-106187887-A | The preparation method of 4 hydroxyquinoline 3 formic acid | 上海工程技术大学 | 2016-12-07 | — | — | CN | disclosed |