Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | RAC1 | P63000 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16647335 | 0.81 | KDM4E (0.39) | HPGDHSD17B10NR1H2NR1H3KDM4E | |
| SCHEMBL22447153 | 0.81 | CACNA1H (0.35) | HPGDHSD17B10UHRF1CACNA1HNR1H2 | |
| SCHEMBL16647331 | 0.78 | LMNA (0.42) | HPGDHTR2AHTR2CCACNA1HKDM4E | |
| SCHEMBL25909026 | 0.77 | RXRA (0.40) | HPGDHSD17B10KDM4E | |
| SCHEMBL29707486 | 0.75 | UHRF1 (0.52) | UHRF1KDM4ELMNANOS3NOS1 | |
| SCHEMBL317221 | 0.75 | UHRF1 (0.52) | UHRF1KDM4ELMNANOS3NOS1 | |
| SCHEMBL15857991 | 0.74 | UHRF1 (0.39) | HPGDHSD17B10UHRF1KDM4EHSP90AA1 | |
| Hydrochloric Acid SCHEMBL5010733 | 0.74 | UHRF1 (0.50) | UHRF1KDM4ELMNANOS3NOS1 | |
| Hydrochloric Acid SCHEMBL18765302 | 0.74 | UHRF1 (0.50) | UHRF1KDM4ELMNANOS3NOS1 | |
| Hydrochloric Acid SCHEMBL29505702 | 0.74 | UHRF1 (0.50) | UHRF1KDM4ELMNANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790160-A | Pyrido 5-membered aromatic cyclics, preparation method and the usage | 上海海和药物研究开发有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105308038-B | The inhibitor of Zeste enhancers homologue 2 | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2018-05-29 | — | — | CN | disclosed |
| CN-106170290-A | Substituted di-amino-pyrimidine based compound, combinations thereof and treatment method thereof | 西格诺药品有限公司 | 2016-11-30 | — | — | CN | disclosed |