Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TNF | P01375 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512278 | 0.78 | — | — | |
| SCHEMBL28116041 | 0.73 | CYP19A1 (0.43) | KMT2ATSHRLMNAHTTMAPK1 | |
| SCHEMBL27751211 | 0.72 | ALDH1A1 (0.50) | KMT2ATSHRLMNAMAPK1ALDH1A1 | |
| SCHEMBL28116008 | 0.72 | PSEN1 (0.39) | KMT2ATSHRLMNAHTTMAPK1 | |
| SCHEMBL28115650 | 0.70 | MAPK1 (0.42) | KMT2ATSHRLMNAMAPK1TNF | |
| SCHEMBL28115648 | 0.70 | TNF (0.39) | KMT2AMAPK1TNFALDH1A1KDM4E | |
| SCHEMBL5183901 | 0.69 | GAA (0.33) | KMT2ATSHRLMNAHTTPDE10A | |
| SCHEMBL9684799 | 0.67 | CYP19A1 (0.42) | TSHRLMNAHTTMAPTPDE10A | |
| SCHEMBL28655721 | 0.66 | ACHE (0.56) | KMT2AMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL30159644 | 0.66 | ACHE (0.56) | KMT2AMAPK1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104412985-B | Apply containing luxuriant and rich with fragrance heterocycle compound and preparation method thereof and Antiphytoviral | 南开大学 | 2016-12-28 | — | — | CN | disclosed |