Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069884 | 0.87 | LMNA (0.55) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL8069859 | 0.84 | LMNA (0.62) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL15708410 | 0.84 | KMT2A (0.48) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL8068275 | 0.84 | LMNA (0.44) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL9949502 | 0.84 | PARP10 (0.43) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL15726676 | 0.82 | KMT2A (0.52) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL8069813 | 0.82 | KMT2A (0.50) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL2907355 | 0.81 | ALDH1A1 (0.50) | LMNAMAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL28905911 | 0.81 | LMNA (0.50) | LMNAMAPTALDH1A1KMT2AHTT | |
| SCHEMBL2574111 | 0.81 | KMT2A (0.44) | LMNAMAPTALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278925-B | A kind of preparation method of Antirheumatic Drug Actarit | 平光制药股份有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-106278925-A | A kind of preparation method of Antirheumatic Drug Actarit | 平光制药股份有限公司 | 2017-01-04 | — | — | CN | disclosed |