Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14464032 | 0.72 | — | — | |
| SCHEMBL598140 | 0.72 | ALDH1A1 (0.52) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL891044 | 0.68 | HMBS (0.39) | ALDH1A1GAAUSP2PKMHPGD | |
| Hydrogen Peroxide SCHEMBL11434421 | 0.68 | ALDH1A1 (0.59) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL1610841 | 0.67 | ALDH1A1 (0.48) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL11602428 | 0.66 | ALDH1A1 (0.47) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL9339775 | 0.66 | ALDH1A1 (0.47) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL27887355 | 0.66 | ESR1 (0.60) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL25618771 | 0.65 | USP2 (0.35) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL891324 | 0.65 | USP2 (0.35) | ALDH1A1GAAUSP2PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164068-A | Isoindolinone compounds as the GPR119 regulator for the treatment of diabetes, obesity, dyslipidemia and associated conditions | 赛诺菲 | 2016-11-23 | — | — | CN | disclosed |