Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866232 | 0.85 | F2 (0.49) | RECQLCACNA1GCACNA1ISMN1; SMN2PKM | |
| SCHEMBL1865930 | 0.84 | LMNA (0.47) | CACNA1GCACNA1HCACNA1ISMN1; SMN2PKM | |
| SCHEMBL1861055 | 0.82 | NPC1 (0.47) | SMN1; SMN2PKMKMT2AALDH1A1TDP1 | |
| SCHEMBL17316603 | 0.81 | HDAC1 (0.49) | CACNA1GCACNA1HCACNA1ISMN1; SMN2PKM | |
| SCHEMBL1068209 | 0.80 | CYP19A1 (0.47) | CYP11B1CYP11B2SMN1; SMN2PKMKMT2A | |
| SCHEMBL27765571 | 0.80 | SMN1; SMN2 (0.46) | RECQLCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL17316399 | 0.80 | HDAC1 (0.50) | SMN1; SMN2PKMKMT2AALDH1A1LMNA | |
| SCHEMBL17316704 | 0.79 | LMNA (0.44) | CACNA1GCACNA1HCACNA1CCACNA1IPKM | |
| SCHEMBL17316539 | 0.78 | LMNA (0.44) | CACNA1GCACNA1HCACNA1ISMN1; SMN2PKM | |
| SCHEMBL25430551 | 0.78 | PKM (0.47) | RECQLCYP11B1SMN1; SMN2PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669558-B | Benzyl -1H- pyrazoles, benzyl -1H- azole derivatives and its preparation method and application | 四川大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |