Pyridine

Pyridine

SCHEMBL28116441

ClC(Cl)(Cl)c1ccccc1.c1ccncc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.70
TDP1 Q9NUW8 2/20 0.45
NAPRT Q6XQN6 1/20 0.45
ALDH1A1 P00352 1/20 0.42
NOTUM Q6P988 1/20 0.40
CYP19A1 P11511 2/20 0.39
CYP1A2 P05177 3/20 0.39
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
HIF1A Q16665 2/20 0.37
KIF11 P52732 1/20 0.37
KCNA5 P22460 1/20 0.37
KCNN4 O15554 3/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorotriphenylmethane SCHEMBL3638985 0.85 CYP19A1 (0.53) TSHRTDP1NAPRTALDH1A1NOTUM
Hydrochloric Acid SCHEMBL28846684 0.84 TSHR (0.88) TSHRALDH1A1CYP1A2CYP11B1CYP11B2
SCHEMBL522316 0.84 TSHR (1.00) TSHRALDH1A1CYP1A2CYP3A4KCNN4
SCHEMBL28106849 0.82 TSHR (0.74) TSHRTDP1ALDH1A1CYP19A1CYP1A2
Methyl Alcohol SCHEMBL28788630 0.81 TSHR (0.82) TSHRALDH1A1CYP1A2CYP3A4CYP2C19
Fluoride SCHEMBL28084339 0.81 TSHR (0.93) TSHRALDH1A1CYP1A2CYP3A4KCNN4
Hydrochloric Acid SCHEMBL27351108 0.81 TSHR (0.93) TSHRALDH1A1CYP1A2CYP3A4KCNN4
SCHEMBL30740351 0.81 TSHR (0.93) TSHRALDH1A1CYP1A2CYP3A4KCNN4
Hydrochloric Acid SCHEMBL28581636 0.81 TSHR (0.93) TSHRALDH1A1CYP1A2CYP3A4KCNN4
Hydrochloric Acid SCHEMBL19409802 0.79 TSHR (0.78) TSHRTDP1ALDH1A1CYP19A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106278765-A A kind of organic soil conditioner 张鸿 2017-01-04 CN claimed
CN-107129383-A A kind of composite safe synergist for improving utilization rate of nitrogen fertilizer 北京中农富源生物工程技术有限公司 2017-09-05 CN disclosed