Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1503396 | 0.84 | ALDH1A1 (0.65) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| Methane SCHEMBL29198074 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| SCHEMBL4705245 | 0.77 | CYP3A4 (0.48) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| SCHEMBL11535771 | 0.77 | CYP3A4 (0.72) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| SCHEMBL29733033 | 0.77 | CYP3A4 (0.48) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| SCHEMBL9772902 | 0.72 | CA1 (0.54) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| SCHEMBL17488259 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| SCHEMBL9387233 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRMAPK1GAA | |
| SCHEMBL5505433 | 0.72 | CD44 (0.44) | ALDH1A1CYP3A4TSHRGAACA1 | |
| SCHEMBL4704877 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TSHRMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | ALDH1A1 401/4885CYP3A4 1909/4885TSHR 3644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.