SCHEMBL1503396

SCHEMBL1503396

Nc1c(Cl)cc(-c2cc(Cl)c(N)c(Cl)c2)cc1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
CYP3A4 P08684 5/20 0.65
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
TTR P02766 1/20 0.47
TSHR P16473 3/20 0.46
MAPK1 P28482 1/20 0.46
GAA P10253 2/20 0.44
AHR P35869 4/20 0.40
TP53 P04637 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
POLB P06746 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL29198074 0.97 ALDH1A1 (0.61) ALDH1A1CYP3A4CA1CA2CA9
SCHEMBL2811649 0.84 ALDH1A1 (0.48) ALDH1A1CYP3A4CA1CA2CA9
SCHEMBL31163138 0.84 CYP3A4 (0.55) ALDH1A1CYP3A4CA1CA2CA9
SCHEMBL4248838 0.84 AHR (0.65) ALDH1A1CYP3A4TSHRMAPK1AHR
SCHEMBL3827276 0.84 ESR2 (0.50) ALDH1A1CYP3A4TSHRMAPK1GAA
SCHEMBL9772902 0.80 CA1 (0.54) ALDH1A1CYP3A4CA1CA2CA9
SCHEMBL1392591 0.80 CYP3A4 (0.65) ALDH1A1CYP3A4CA1CA2CA9
SCHEMBL657760 0.79 ALDH1A1 (0.65) ALDH1A1CYP3A4CA1CA2CA9
SCHEMBL292270 0.79 CYP3A4 (1.00) ALDH1A1CYP3A4CA1CA2CA9
Hydrochloric Acid SCHEMBL11784583 0.76 ALDH1A1 (0.61) ALDH1A1CYP3A4CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0485474-A1 A METHOD AND A SYSTEM FOR QUANTITATIVELY MONITORING A CHEMICAL COMPONENT DISSOLVED IN A LIQUID MEDIUM. KOEGE KEMISK VAERK (DK) 1992-05-20 EP claimed
WO-1991002254-A1 A METHOD AND A SYSTEM FOR QUANTITATIVELY MONITORING A CHEMICAL COMPONENT DISSOLVED IN A LIQUID MEDIUM KEMISK VÆRK KØGE A/S (DK) 1991-02-21 WO claimed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US claimed
US-4002584-A LONG CHAIN POLYOL, HALOGENATED AROMATIC DIAMINE, ONE-SHOT REACTION IHARA CHEMICAL KOGYO KABUSHIKI KAISHA (JA) 1977-01-11 US claimed
US-20260131280-A1 GAS SEPARATION MEMBRANE UNIT, GAS SEPARATION SYSTEM, AND METHOD FOR PRODUCING ENRICHED GAS UBE CORP (JP) 2026-05-14 US disclosed
EP-4721843-A1 GAS SEPARATION MEMBRANE UNIT, GAS SEPARATION SYSTEM, AND METHOD FOR PRODUCING ENRICHED GAS UBE Corporation (JP) 2026-04-08 EP disclosed
EP-4691603-A1 GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING METHANE ENRICHED GAS UBE Corporation (JP) 2026-02-11 EP disclosed
US-20260008003-A1 GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING METHANE-ENRICHED GAS UBE CORP (JP) 2026-01-08 US disclosed
WO-2025100202-A1 POLYIMIDE, AND POLYIMIDE THIN FILM 本州化学工業株式会社 2025-05-15 WO disclosed
US-20240376267-A1 POLYIMIDE RESIN MATERIAL FOR COLORLESS TRANSPARENT PROCESSED PRODUCT AND NOVEL POLYIMIDE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2024-11-14 US disclosed
WO-2024101441-A1 POLYIMIDE, POLYIMIDE THIN FILM 本州化学工業株式会社 2024-05-16 WO disclosed
WO-2024101442-A1 POLYIMIDE, POLYIMIDE THIN FILM, AND POLYIMIDE MATERIAL FOR ELECTRONIC APPARATUS/DEVICE 本州化学工業株式会社 2024-05-16 WO disclosed
EP-0035654-A2 Dyestuff compositions, process for their preparation and their use in dyeing synthetic materials BAYER AG (DE) 1981-09-16 EP disclosed
US-4222788-A Mixed pigment and process of preparing the same BASF FARBEN & FASERN AG (DE) 1980-09-16 US disclosed
EP-0008058-A1 N-Amino-3,4,5-trihydroxypiperidines, methods for their preparation, medicaments containing them, method for the production of the medicaments and animal feedstuff containing said compounds BAYER AG (DE) 1980-02-20 EP disclosed
US-4165319-A Isoindoline pigments CIBA-GEIGY CORPORATION (US) 1979-08-21 US disclosed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US disclosed
US-4065448-A Tertiary alkyl substituted disazo pigments CIBA-GEIGY AG (CH) 1977-12-27 US disclosed
US-4053464-A DISAZO PIGMENTS CONTAINING ETHER SUBSTITUTED ALKOXY CARBONYL GROUPS CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4002584-A LONG CHAIN POLYOL, HALOGENATED AROMATIC DIAMINE, ONE-SHOT REACTION IHARA CHEMICAL KOGYO KABUSHIKI KAISHA (JA) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131280-A1 GAS SEPARATION MEMBRANE UNIT, GAS SEPARATION SYSTEM, AND METHOD FOR PRODUCING ENRICHED GAS SCO2, SLC2A4, STOML2 ALDH1A1 4807/4885CYP3A4 1207/4885CA1 1370/4885
US-20260008003-A1 GAS SEPARATION SYSTEM AND METHOD FOR PRODUCING METHANE-ENRICHED GAS SCO2, MT-CO2, SLC2A4 ALDH1A1 4665/4885CYP3A4 435/4885CA1 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.