SCHEMBL28116501

SCHEMBL28116501

NC1CCc2c(ccc3c2ccc2ccccc23)C1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 3/20 0.47
DRD3 P35462 3/20 0.47
PLAU P00749 1/20 0.47
ANPEP P15144 1/20 0.47
HPRT1 P00492 1/20 0.44
HTR1A P08908 2/20 0.42
HTR7 P34969 2/20 0.42
NR2E1 Q9Y466 1/20 0.41
HTR6 P50406 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28095840 0.88 PLAU (0.47) DRD2DRD3PLAUANPEPHPRT1
Isoquinoline SCHEMBL27294345 0.86 DRD2 (0.37) DRD2DRD3PLAUANPEPHTR1A
Beta-Naphtoic Acid SCHEMBL27806332 0.84 SIRT2 (0.39) DRD2DRD3ANPEPHTR6
SCHEMBL27497738 0.81 HPRT1 (0.44) ANPEPHPRT1HTR1AHTR7
SCHEMBL27301903 0.81 HPRT1 (0.44) ANPEPHPRT1HTR1AHTR7
SCHEMBL27574172 0.81 HTR7 (0.45) ANPEPHPRT1HTR1AHTR7
SCHEMBL28081883 0.81 HPRT1 (0.44) ANPEPHPRT1HTR1AHTR7
SCHEMBL28063838 0.81 ANPEP (0.40) ANPEPHPRT1HTR1AHTR7
SCHEMBL28063782 0.81 ANPEP (0.40) ANPEPHPRT1HTR1AHTR7
Fluoride SCHEMBL27587185 0.80 HTR7 (0.44) ANPEPHPRT1HTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106946748-A Deliver method, compound, composition and the carrier of the propane sulfonic acid of 3 amino 1 BHI有限合资公司 2017-07-14 CN disclosed
CN-103787927-B Deliver method, compound, compositionss and the carrier of 3 amino 1 propane sulfonic acid BHI有限合资公司 2017-03-01 CN disclosed
CN-104693205-B Total synthesis method of amides alkaloid 西安交通大学 2017-02-01 CN disclosed