SCHEMBL28116522

SCHEMBL28116522

C=C(CCC[Si](C)(C)C)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 2/20 0.33
TET2 Q6N021 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28109390 0.88 ALDH1A1 (0.41) ALDH1A1TSHRTET2EGLN1
SCHEMBL7924271 0.83 TSHR (0.48) ALDH1A1TSHRTET2EGLN1RECQL
SCHEMBL27781934 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11603931 0.78 ALDH1A1 (0.52) ALDH1A1TSHRTET2EGLN1RECQL
SCHEMBL27553829 0.77 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL18210535 0.77 ALDH1A1 (0.35) ALDH1A1TSHRTET2EGLN1RECQL
SCHEMBL998271 0.77 ALDH1A1 (0.42) ALDH1A1TSHRTET2EGLN1RECQL
SCHEMBL1298659 0.77 CES1 (0.44) ALDH1A1TSHR
SCHEMBL225184 0.77 TBXAS1 (0.39) TET2
SCHEMBL10579259 0.75 TSHR (0.42) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106232649-B Rheology modifier polymer 罗地亚经营管理公司 2019-08-13 CN disclosed
CN-106232649-A Rheology modifier polymer 罗地亚经营管理公司 2016-12-14 CN disclosed