SCHEMBL28116639

SCHEMBL28116639

[CH2]c1cccc(CO)c1CO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APOBEC3G Q9HC16 1/20 0.38
GABRA1 P14867 2/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
LMNA P02545 2/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GABRB2 P47870 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27388 0.82 APOBEC3G (0.46) APOBEC3GGABRA1GABRG2GABRB3PDCD1
Benzene SCHEMBL7199484 0.79 PDCD1 (0.46) APOBEC3GGABRA1GABRG2GABRB3PDCD1
SCHEMBL232082 0.77
SCHEMBL3446153 0.76 HSD17B10 (0.38) GABRA1GABRG2GABRB3LMNAHPGD
SCHEMBL29197346 0.76 KDM4E (0.38) APOBEC3GGABRA1GABRG2GABRB3PDCD1
SCHEMBL11862358 0.75 APOBEC3G (0.41) APOBEC3GGABRA1GABRG2GABRB3PDCD1
SCHEMBL8478408 0.74 AKR1B1 (0.43) GABRA1GABRG2GABRB3LMNAGAA
SCHEMBL5213557 0.74 PNMT (0.37) APOBEC3GGABRA1PDCD1CD274HPGD
SCHEMBL10563090 0.74 APOBEC3G (0.44) APOBEC3GGABRA1GABRG2GABRB3PDCD1
SCHEMBL30182764 0.73 HSPA5 (0.44) APOBEC3GGABRA1GABRG2GABRB3PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279162-A One-dimensional organic semiconductor nanowires/band that organophosphorus compound toxic gas is had fluorescence response and its preparation method and application 中国科学院化学研究所 2017-01-04 CN claimed
CN-106279162-A One-dimensional organic semiconductor nanowires/band that organophosphorus compound toxic gas is had fluorescence response and its preparation method and application 中国科学院化学研究所 2017-01-04 CN disclosed