Benzene

Benzene

SCHEMBL7199484

OCc1cccc(CO)c1CO.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1.c1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
APOBEC3G Q9HC16 1/20 0.44
GABRA1 P14867 2/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
TSHR P16473 2/20 0.41
HDAC3 O15379 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HPGD P15428 3/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GABRB2 P47870 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27388 0.97 APOBEC3G (0.46) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL11862358 0.89 APOBEC3G (0.41) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL2651606 0.85 IDO1 (0.39) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL28116266 0.85 PNMT (0.43) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL28116641 0.85 APOBEC3G (0.38) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL17417172 0.85 GABRA1 (0.52) PDCD1CD274APOBEC3GGABRA1GABRG2
Propiolic Acid SCHEMBL31720857 0.82 HDAC3 (0.36) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL167807 0.81 HSPA5 (0.44) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL30182764 0.81 HSPA5 (0.44) PDCD1CD274APOBEC3GGABRA1GABRG2
SCHEMBL30140762 0.81 PDCD1 (0.62) PDCD1CD274APOBEC3GHDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6596874-B1 Salt formation by reaction using benzenesulfonic acid RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2003-07-22 US disclosed