Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17316707 | 0.87 | PKM (0.43) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL21199265 | 0.86 | SOS1 (0.52) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL17316371 | 0.84 | LMNA (0.46) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL17316704 | 0.82 | LMNA (0.44) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL17316556 | 0.81 | KMT2A (0.48) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL17316675 | 0.81 | LMNA (0.39) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL1866232 | 0.80 | F2 (0.49) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL17316547 | 0.79 | LMNA (0.47) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL17316377 | 0.79 | LMNA (0.47) | PKMPOLBALDH1A1LMNAKMT2A | |
| SCHEMBL17316603 | 0.79 | HDAC1 (0.49) | PKMPOLBALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669558-B | Benzyl -1H- pyrazoles, benzyl -1H- azole derivatives and its preparation method and application | 四川大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |