Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA4 | P22748 | 3/20 | 0.59 |
| ▸ | CA6 | P23280 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GPR3 | P46089 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL974181 | 0.96 | CA1 (0.63) | CA1CA2CA4CA6ALDH1A1 | |
| Fluorene SCHEMBL29283448 | 0.96 | CA1 (0.63) | CA1CA2CA4CA6ALDH1A1 | |
| Fluorene SCHEMBL27883882 | 0.94 | CA1 (0.61) | CA1CA2CA4CA6ALDH1A1 | |
| Anthrone SCHEMBL28721809 | 0.85 | MAOA (0.67) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL30116551 | 0.84 | KIF11 (0.56) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL11992354 | 0.84 | KIF11 (0.56) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL30631720 | 0.84 | KIF11 (0.56) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL11992353 | 0.84 | KIF11 (0.56) | CA1CA2CA4CA6ALDH1A1 | |
| Carbazole SCHEMBL20527135 | 0.81 | CA1 (0.64) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL17206856 | 0.81 | KIF11 (0.53) | CA1CA2CA4CA6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220553-A | Carbazole-fluorene ethylene derivatives and synthetic method thereof | 沈阳大学 | 2016-12-14 | — | — | CN | claimed |
| CN-106220553-A | Carbazole-fluorene ethylene derivatives and synthetic method thereof | 沈阳大学 | 2016-12-14 | — | — | CN | disclosed |
| CN-106220553-A | Carbazole-fluorene ethylene derivatives and synthetic method thereof | 沈阳大学 | 2016-12-14 | — | — | CN | disclosed |
| CN-106220553-A | Carbazole-fluorene ethylene derivatives and synthetic method thereof | 沈阳大学 | 2016-12-14 | — | — | CN | disclosed |