Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28123064 | 0.86 | ALDH1A1 (0.46) | PTPN1ALDH1A1HTTMAOBTSHR | |
| SCHEMBL28122447 | 0.85 | PTPN1 (0.42) | PTPN1ALDH1A1HTTMAOBTSHR | |
| SCHEMBL28150725 | 0.82 | ALDH1A1 (0.40) | PTPN1ALDH1A1HTTMAOBTSHR | |
| SCHEMBL28121153 | 0.82 | CA12 (0.40) | PTPN1ALDH1A1HTTTSHRMAPT | |
| SCHEMBL28138656 | 0.80 | PTPN1 (0.39) | PTPN1ALDH1A1HTTMAOBTSHR | |
| SCHEMBL2269352 | 0.77 | ALDH1A1 (0.37) | PTPN1ALDH1A1HTTMAOBL3MBTL1 | |
| SCHEMBL29287438 | 0.77 | PTPN1 (0.37) | PTPN1ALDH1A1HTTMAOBTSHR | |
| SCHEMBL30266542 | 0.77 | KDM4E (0.55) | PTPN1ALDH1A1HTTMAOBTSHR | |
| SCHEMBL28233144 | 0.76 | POLB (0.41) | PTPN1ALDH1A1HTTMAPTHPGD | |
| SCHEMBL28121149 | 0.76 | PTPN1 (0.36) | PTPN1HTTMAOBTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279082-B | Substituted furans chalcone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-106905340-B | Benzofuran fluoro flavanone derivative and preparation method thereof | 浙江大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-106336417-A | Substituted furan isoflavone derivative and preparation method thereof | 浙江大学 | 2017-01-18 | — | — | CN | disclosed |
| CN-106279082-A | Substituted furan chalcone derivant and preparation method thereof | 浙江大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-106243121-A | Substituted furan-flavone alcohol derivatives and preparation method thereof | 浙江大学 | 2016-12-21 | — | — | CN | disclosed |