Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29287438 | 0.86 | PTPN1 (0.37) | PTPN1TSHRHTTKDM4EMEN1 | |
| SCHEMBL28123064 | 0.83 | ALDH1A1 (0.46) | PTPN1TSHRHPGDHTTKDM4E | |
| SCHEMBL28150725 | 0.82 | ALDH1A1 (0.40) | PTPN1TSHRHTTKDM4EMEN1 | |
| SCHEMBL28116761 | 0.80 | PTPN1 (0.56) | PTPN1TSHRHPGDHTTALOX15 | |
| SCHEMBL28121149 | 0.79 | PTPN1 (0.36) | PTPN1TSHRHTTMEN1KMT2A | |
| SCHEMBL28121153 | 0.79 | CA12 (0.40) | PTPN1TSHRHPGDHTTKDM4E | |
| SCHEMBL28122447 | 0.78 | PTPN1 (0.42) | PTPN1TSHRHPGDHTTALOX15 | |
| SCHEMBL28845327 | 0.73 | NPC1 (0.52) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL28306563 | 0.73 | NPC1 (0.52) | KDM4EMEN1KMT2AALDH1A1PKM | |
| SCHEMBL28305435 | 0.73 | KMT2A (0.38) | PTPN1TSHRHPGDHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905340-A | Benzofuran fluoro flavanone derivative and preparation method thereof | 浙江大学 | 2017-06-30 | — | — | CN | disclosed |