Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152622 | 0.76 | GRM5 (0.49) | KCNH2GRM5CYP1A2CREBBPBRD4 | |
| SCHEMBL11246729 | 0.76 | GRM5 (0.49) | KCNH2GRM5CYP1A2CREBBPBRD4 | |
| SCHEMBL11236538 | 0.74 | GRM5 (0.46) | PGK1KCNH2GRM5CYP1A2CREBBP | |
| SCHEMBL31125221 | 0.71 | CYP3A4 (0.42) | PGK1 | |
| SCHEMBL2806703 | 0.70 | KCNH2 (0.47) | KCNH2GRM5CYP1A2CREBBPBRD4 | |
| SCHEMBL11235967 | 0.69 | GRM5 (0.49) | KCNH2GRM5CYP1A2CREBBPBRD4 | |
| SCHEMBL2811696 | 0.69 | FFAR1 (0.36) | KCNH2GRM5CYP1A2FFAR1FFAR4 | |
| SCHEMBL21722829 | 0.68 | NOS2 (0.41) | PGK1 | |
| SCHEMBL1921609 | 0.67 | GABRA1 (0.40) | PGK1 | |
| SCHEMBL11237060 | 0.67 | KCNH2 (0.51) | KCNH2GRM5CYP1A2CREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | TRPV4 2447/4885PGK1 3615/4885KCNH2 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.