Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955018 | 0.81 | NFE2L2 (0.35) | HTR2ASLC6A4KCNH2MAPTRAB9A | |
| SCHEMBL16960097 | 0.81 | PKM (0.33) | KCNH2MAPTRAB9ANPC1HPGD | |
| SCHEMBL16959212 | 0.79 | NPC1 (0.33) | MAPTRAB9ANPC1HPGDHTT | |
| SCHEMBL5404806 | 0.78 | NFE2L2 (0.36) | MAPTRAB9ANPC1HPGDHTT | |
| SCHEMBL16950754 | 0.78 | NPC1 (0.33) | HTR2ASLC6A4KCNH2MAPTRAB9A | |
| SCHEMBL16953081 | 0.78 | NPSR1 (0.35) | MAPTRAB9ANPC1HPGDHTT | |
| SCHEMBL15157476 | 0.76 | NPC1 (0.37) | MAPTRAB9ANPC1HPGDHTT | |
| SCHEMBL16956621 | 0.76 | NPC1 (0.34) | HTR2ASLC6A4MAPTRAB9ANPC1 | |
| SCHEMBL16957954 | 0.75 | F2RL1 (0.40) | MAPTRAB9ANPC1HPGDHTT | |
| SCHEMBL16957951 | 0.75 | NPC1 (0.35) | MAPTRAB9ANPC1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | claimed |
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | disclosed |