Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627248 | 0.86 | PDE2A (0.50) | MAPTL3MBTL1ALDH1A1MAPK1FYN | |
| SCHEMBL28837591 | 0.86 | TUBB4A (0.54) | MAPTFYNCHEK2MEN1KMT2A | |
| SCHEMBL28117707 | 0.83 | FYN (0.50) | FYNCHEK2 | |
| SCHEMBL28117798 | 0.83 | FYN (0.55) | MAPTALDH1A1FYNPDGFRBCHEK2 | |
| SCHEMBL28118129 | 0.82 | EPHB4 (0.46) | MAPTALDH1A1MAPK1FYNPDGFRB | |
| SCHEMBL28118150 | 0.80 | FYN (0.46) | FYNCHEK2 | |
| SCHEMBL28118147 | 0.80 | FYN (0.58) | ALDH1A1FYNCHEK2 | |
| SCHEMBL28117789 | 0.78 | ABCB1 (0.50) | MAPTALDH1A1MAPK1 | |
| SCHEMBL28117665 | 0.75 | ABCB1 (0.45) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28837693 | 0.73 | MGAM (0.53) | MAPTMAPK1FYNMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279058-A | The preparation of 3,4-diaryl-1,2,5-diazole oxide and purposes | 沈阳药科大学 | 2017-01-04 | — | — | CN | disclosed |