Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366004 | 0.87 | TNKS2 (0.46) | TNKS2SMN1; SMN2ALOX5PTGS2TSHR | |
| SCHEMBL28117674 | 0.78 | KDM4E (0.40) | TSHRKDM4EALDH1A1CYP1A2POLB | |
| SCHEMBL5782701 | 0.75 | TP53 (0.46) | SMN1; SMN2ALOX5PTGS2TSHRL3MBTL1 | |
| SCHEMBL6172042 | 0.74 | ALOX5 (0.50) | TNKS2SMN1; SMN2ALOX5PTGS2LMNA | |
| SCHEMBL8986937 | 0.73 | TNKS2 (0.43) | TNKS2SMN1; SMN2ALOX5TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9710312 | 0.73 | TAAR1 (0.40) | SMN1; SMN2LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5879461 | 0.71 | CA1 (0.40) | TNKS2KDM4EPOLBCA1CA2 | |
| SCHEMBL28691569 | 0.71 | PTGS2 (0.59) | ALOX5PTGS2 | |
| SCHEMBL505777 | 0.71 | CA1 (0.50) | SMN1; SMN2TSHRL3MBTL1LMNAKDM4E | |
| SCHEMBL80578 | 0.71 | TAAR1 (0.60) | ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317898-A | Photocured organosilicone elastomer and preparation method and application thereof | 广东工业大学 | 2017-01-11 | — | — | CN | disclosed |