Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | STAT1 | P42224 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336730 | 0.92 | KDM4E (0.67) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL20119309 | 0.90 | TDP1 (0.69) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL5085785 | 0.88 | KMT2A (0.81) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL6759722 | 0.87 | KDM4E (0.53) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL28895934 | 0.87 | KMT2A (0.68) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL1787512 | 0.83 | HCAR2 (0.67) | KDM4EMAPTCYP1A2CYP2D6CYP2C9 | |
| Benzyl Benzoate SCHEMBL901058 | 0.82 | KMT2A (1.00) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| Benzyl Benzoate SCHEMBL3038 | 0.82 | KMT2A (1.00) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| Benzyl Benzoate SCHEMBL8010992 | 0.82 | KMT2A (1.00) | KMT2ATDP1SLC6A2SLC6A3KDM4E | |
| SCHEMBL6667657 | 0.82 | TDP1 (0.71) | KMT2ATDP1SLC6A2SLC6A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11618748-B2 | Dual mechanism inhibitors for the treatment of disease | AERIE PHARMACEUTICALS, INC. (US) | 2023-04-04 | — | — | US | disclosed |
| CN-103261156-B | For treating the noval chemical compound of neurodegenerative disease | 鲁汶天主教大学研究开发部 | 2016-12-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11618748-B2 | Dual mechanism inhibitors for the treatment of disease | RHOA, SLC6A2, ROCK2 | KMT2A 3013/4885TDP1 890/4885SLC6A2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.