SCHEMBL28117929

SCHEMBL28117929

Fc1cc2cc(Cl)ccc2o1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.55
KDM4E B2RXH2 5/20 0.47
GPR35 Q9HC97 2/20 0.47
CYP1A2 P05177 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP2C9 P11712 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
KMT2A Q03164 1/20 0.46
CA12 O43570 1/20 0.46
CA9 Q16790 1/20 0.46
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
HSD17B10 Q99714 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14231749 0.77 MAOB (0.59) MAOBKDM4EGPR35CYP1A2ALDH1A1
SCHEMBL434464 0.74 MAOB (0.55) MAOBKDM4EGPR35CYP1A2ALDH1A1
SCHEMBL25824461 0.74 MAOB (0.55) MAOBKDM4EGPR35CYP1A2ALDH1A1
SCHEMBL15031529 0.74 MAOB (0.55) MAOBKDM4EGPR35CYP1A2ALDH1A1
SCHEMBL15031527 0.74 MAOB (0.55) MAOBKDM4EGPR35CYP1A2ALDH1A1
SCHEMBL23920139 0.74 MAOB (0.55) MAOBKDM4EGPR35CYP1A2ALDH1A1
SCHEMBL2090135 0.74 MAOB (0.55) MAOBKDM4EGPR35CYP1A2ALDH1A1
SCHEMBL29608860 0.74 CYP2A6 (0.53) MAOBGPR35ALDH1A1CA1CA2
SCHEMBL3928306 0.74 CYP2A6 (0.53) MAOBGPR35ALDH1A1CA1CA2
SCHEMBL23241640 0.74 ALDH1A1 (0.52) MAOBCYP1A2ALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397377-A Electron-rich five-membered heterocyclic acid and method for decarboxylation and fluorination of derivative thereof 中南大学 2017-02-15 CN disclosed