Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.75 |
| ▸ | KDM4A | O75164 | 2/20 | 0.75 |
| ▸ | KDM6B | O15054 | 1/20 | 0.75 |
| ▸ | KDM5C | P41229 | 1/20 | 0.75 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.75 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.75 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.64 |
| ▸ | CCR1 | P32246 | 2/20 | 0.64 |
| ▸ | CCR5 | P51681 | 2/20 | 0.64 |
| ▸ | CCR8 | P51685 | 2/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | METAP1 | P53582 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL6037611 | 0.90 | KDM4E (0.69) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| Benzoic Acid SCHEMBL30567494 | 0.89 | KDM4C (0.96) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| Dipyridyl SCHEMBL2792069 | 0.88 | KDM4E (0.74) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| Dipyridyl SCHEMBL30976994 | 0.88 | KDM4E (0.74) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| Dipyridyl SCHEMBL18601618 | 0.88 | KDM4E (0.74) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| Dipyridyl SCHEMBL7773433 | 0.88 | KDM4E (0.74) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| SCHEMBL5858 | 0.88 | KDM4E (0.61) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| SCHEMBL29788328 | 0.88 | KDM4E (0.61) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| SCHEMBL863317 | 0.86 | KDM4E (0.74) | KDM4EKDM4AKDM6BKDM5CKDM4C | |
| Dipyridyl SCHEMBL21551506 | 0.86 | KDM4C (1.00) | KDM4EKDM4AKDM6BKDM5CKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188107-A | Multi-functional zinc-base organic-inorganic hybrid material, its preparation method and application | 郑州轻工业学院 | 2016-12-07 | — | — | CN | claimed |
| CN-108658849-B | Cr (III) complex and preparation method and application thereof | 太原师范学院 | 2021-08-13 | — | — | CN | disclosed |
| CN-108658849-A | A kind of Cr (III) complex and its preparation method and application | 太原师范学院 | 2018-10-16 | — | — | CN | disclosed |
| CN-106188107-B | Multi-functional zinc-base organic-inorganic hybrid material, its preparation method and application | 郑州轻工业学院 | 2017-11-10 | — | — | CN | disclosed |
| CN-106188107-A | Multi-functional zinc-base organic-inorganic hybrid material, its preparation method and application | 郑州轻工业学院 | 2016-12-07 | — | — | CN | disclosed |