SCHEMBL863317

SCHEMBL863317

O=C(O)c1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.74
KDM4A O75164 2/20 0.74
KDM6B O15054 1/20 0.74
KDM5C P41229 1/20 0.74
KDM4C Q9H3R0 1/20 0.74
KDM2A Q9Y2K7 1/20 0.74
KDM3A Q9Y4C1 1/20 0.74
PIN1 Q13526 1/20 0.58
CCR1 P32246 3/20 0.56
CCR5 P51681 3/20 0.56
CCR8 P51685 3/20 0.56
LMNA P02545 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
TP53 P04637 1/20 0.55
ALPL P05186 1/20 0.55
HSP90AA1 P07900 1/20 0.55
ALPI P09923 1/20 0.55
ALPG P10696 1/20 0.55
ALOX15 P16050 1/20 0.55
MAPK1 P28482 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29904774 1.00 KDM4E (0.74) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL28268713 0.93 KDM4E (0.66) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL863220 0.93 KDM5C (0.87) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL29766771 0.86 KDM5C (0.87) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL10000745 0.86 KDM5C (0.87) KDM4EKDM4AKDM6BKDM5CKDM4C
Dipyridyl SCHEMBL28117961 0.86 KDM4E (0.75) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL913277 0.85 KDM4C (1.00) KDM4EKDM4AKDM6BKDM5CKDM4C
SCHEMBL29562841 0.85 KDM4C (1.00) KDM4EKDM4AKDM6BKDM5CKDM4C
Dipyridyl SCHEMBL21551506 0.85 KDM4C (1.00) KDM4EKDM4AKDM6BKDM5CKDM4C
Dipyridyl SCHEMBL3941503 0.85 KDM4C (1.00) KDM4EKDM4AKDM6BKDM5CKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12117571-B2 Metal-organic hybrid lattice material and use thereof in detection of radiation sources SHANGHAI INSTITUTE OF APPLIED PHYSICS CHINESE ACADEMY OF SCIENCES (CN) 2024-10-15 US claimed
US-20220308241-A1 METAL-ORGANIC HYBRID LATTICE MATERIAL AND USE THEREOF IN DETECTION OF RADIATION SOURCES SHANGHAI INSTITUTE OF APPLIED PHYSICS CHINESE ACADEMY OF SCIENCES (CN) 2022-09-29 US claimed
US-12117571-B2 Metal-organic hybrid lattice material and use thereof in detection of radiation sources SHANGHAI INSTITUTE OF APPLIED PHYSICS CHINESE ACADEMY OF SCIENCES (CN) 2024-10-15 US disclosed
US-20220308241-A1 METAL-ORGANIC HYBRID LATTICE MATERIAL AND USE THEREOF IN DETECTION OF RADIATION SOURCES SHANGHAI INSTITUTE OF APPLIED PHYSICS CHINESE ACADEMY OF SCIENCES (CN) 2022-09-29 US disclosed
EP-3127899-B1 RAPID METHOD FOR MEASURING CYTOTOXICITY IN NON-RI SYSTEM UNIV NAGASAKI (JP) 2019-05-08 EP disclosed
US-10175229-B2 Rapid method for measuring cytotoxicity in non-RI system NAGASAKI UNIVERSITY (JP) 2019-01-08 US disclosed
EP-3127899-A1 RAPID METHOD FOR MEASURING CYTOTOXICITY IN NON-RI SYSTEM Nagasaki University (JP) 2017-02-08 EP disclosed
US-20170016880-A1 RAPID METHOD FOR MEASURING CYTOTOXICITY IN NON-RI SYSTEM NAGASAKI UNIVERSITY (JP) 2017-01-19 US disclosed
US-20170016880-A1 RAPID METHOD FOR MEASURING CYTOTOXICITY IN NON-RI SYSTEM NAGASAKI UNIVERSITY (JP) 2017-01-19 US disclosed
US-8759521-B2 Panchromatic photosensitizers and dye-sensitized solar cell using the same NATIONAL TSING HUA UNIVERSITY (TW) 2014-06-24 US disclosed
US-8759521-B2 Panchromatic photosensitizers and dye-sensitized solar cell using the same NATIONAL TSING HUA UNIVERSITY (TW) 2014-06-24 US disclosed
US-20110155238-A1 PYRIDINE TYPE METAL COMPLEX, PHOTOELECTRODE COMPRISING THE METAL COMPLEX, AND DYE-SENSITIZED SOLAR CELL COMPRISING THE PHOTOELECTRODE SHARP KABUSHIKI KAISHA (JP) 2011-06-30 US disclosed
US-20110155238-A1 PYRIDINE TYPE METAL COMPLEX, PHOTOELECTRODE COMPRISING THE METAL COMPLEX, AND DYE-SENSITIZED SOLAR CELL COMPRISING THE PHOTOELECTRODE SHARP KABUSHIKI KAISHA (JP) 2011-06-30 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
EP-2275494-A1 PYRIDINE-TYPE METAL COMPLEX, PHOTOELECTRODE COMPRISING THE METAL COMPLEX, AND DYE-SENSITIZED SOLAR CELL COMPRISING THE PHOTOELECTRODE Sharp Kabushiki Kaisha (JP) 2011-01-19 EP disclosed
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2010-10-14 US disclosed
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2010-10-14 US disclosed
US-20100091352-A1 DISPLAY ELEMENT AND DRIVING METHOD THEREOF KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20100091352-A1 DISPLAY ELEMENT AND DRIVING METHOD THEREOF KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170016880-A1 RAPID METHOD FOR MEASURING CYTOTOXICITY IN NON-RI SYSTEM MKI67, HRH4, NR4A3 KDM4E 1489/4885KDM4A 641/4885KDM6B 2800/4885
US-10175229-B2 Rapid method for measuring cytotoxicity in non-RI system MKI67, HRH4, NR4A3 KDM4E 1489/4885KDM4A 641/4885KDM6B 2800/4885
US-20110155238-A1 PYRIDINE TYPE METAL COMPLEX, PHOTOELECTRODE COMPRISING THE METAL COMPLEX, AND DYE-SENSITIZED SOLAR CELL COMPRISING THE PHOTOELECTRODE CD4, AP1M1, CRY1 KDM4E 481/4885KDM4A 301/4885KDM6B 877/4885
US-20100258175-A1 PANCHROMATIC PHOTOSENSITIZERS AND DYE-SENSITIZED SOLAR CELL USING THE SAME MLX, PRXL2A, MSL1 KDM4E 835/4885KDM4A 866/4885KDM6B 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.