Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.96 |
| ▸ | KDM5C | P41229 | 9/20 | 0.96 |
| ▸ | KDM4A | O75164 | 8/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.96 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.96 |
| ▸ | KDM3A | Q9Y4C1 | 5/20 | 0.96 |
| ▸ | KDM6B | O15054 | 4/20 | 0.96 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.65 |
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.57 |
| ▸ | KDM4B | O94953 | 4/20 | 0.57 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.55 |
| ▸ | KDM5A | P29375 | 5/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | TET3 | O43151 | 1/20 | 0.52 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ASPH | Q12797 | 1/20 | 0.52 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.52 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562841 | 0.98 | KDM4C (1.00) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL913277 | 0.98 | KDM4C (1.00) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| Dipyridyl SCHEMBL21551506 | 0.98 | KDM4C (1.00) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| Dipyridyl SCHEMBL3941503 | 0.98 | KDM4C (1.00) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| Dipyridyl SCHEMBL3954422 | 0.96 | KDM4C (0.96) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| Dipyridyl SCHEMBL8358045 | 0.96 | KDM4C (0.96) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL863220 | 0.92 | KDM5C (0.87) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL10000745 | 0.92 | KDM5C (0.87) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL29668070 | 0.92 | KDM4C (0.87) | KDM4CKDM5CKDM4AKDM4EKDM2A | |
| SCHEMBL29766771 | 0.92 | KDM5C (0.87) | KDM4CKDM5CKDM4AKDM4EKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744909-A | Metal organic frameworks deliver small and biological macromolecules for cancer immunotherapy | 芝加哥大学 | 2023-09-12 | — | — | CN | disclosed |