Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.81 |
| ▸ | BCHE | P06276 | 3/20 | 0.81 |
| ▸ | ACHE | P22303 | 3/20 | 0.81 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384266 | 0.90 | NOX1 (1.00) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL236458 | 0.90 | NOX1 (1.00) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL4706434 | 0.90 | NOX1 (0.68) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL28679021 | 0.88 | NOX1 (0.96) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL29276729 | 0.84 | NOX1 (0.65) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL28635096 | 0.84 | NOX1 (0.65) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL1855994 | 0.84 | NOX1 (0.65) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL11539366 | 0.84 | NOX1 (0.65) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL1509893 | 0.82 | NOX1 (0.84) | NOX1BCHEACHEGAAMAPT | |
| SCHEMBL9778312 | 0.81 | NOX1 (0.70) | NOX1BCHEACHEGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327028-B | Phenothiazine derivative, pharmaceutical composition and application thereof in treating echinococcosis | 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) | 2024-07-23 | — | — | CN | disclosed |
| CN-117327028-A | Phenothiazine derivative, pharmaceutical composition and application thereof in treating echinococcosis | 中国疾病预防控制中心寄生虫病预防控制所(国家热带病研究中心) | 2024-01-02 | — | — | CN | disclosed |
| CN-104311508-B | Synthetic method of iron-catalyzed phenothiazine compound | 苏州大学 | 2017-01-11 | — | — | CN | disclosed |