Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | GAA | P10253 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | CYBB | P04839 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | SNCA | P37840 | 1/20 | 0.70 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.70 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.70 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342449 | 0.83 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| Phenothiazine SCHEMBL28073776 | 0.83 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL29375737 | 0.83 | NOX1 (1.00) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL28117966 | 0.81 | NOX1 (0.81) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL9474653 | 0.81 | NOX1 (0.60) | NOX1MAPTGAAMEN1KMT2A | |
| Ethylene SCHEMBL10370327 | 0.80 | NOX1 (0.94) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL27344712 | 0.78 | ALOX5 (0.51) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1855994 | 0.78 | NOX1 (0.65) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL9778291 | 0.77 | MAPT (0.57) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL28476906 | 0.76 | MAPT (0.58) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036067-A | Enzyme inhibotors | MERCK & CO., INC. (US) | 1991-07-30 | — | — | US | disclosed |